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CD73, Mouse Anti Human
| Catalogue Number | ANT-414 |
| Synonyms | 5'-nucleotidase, Ecto-5'-nucleotidase, 5'-NT, CD73, NT5E, NT5, NTE, NT, eN, eNT, E5NT. |
| Type | Mouse Anti Human Monoclonal. |
| Introduction | Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP at a neutral pH. CD73, which consists of a dimer of 2 identical 70kDa subunits, is bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases. Additional forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. |
| Clone | P2B6AT. |
| Immunogen | Anti-human CD73 mAb , is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CD73 amino acids 27-252 purified from E. coli. |
| Ig Subclass | Mouse IgG2b heavy chain and κ light chain. |
| Purification Method | CD73 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Physical Appearance | Sterile filtered colorless solution. |
| Protein formulation | 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. |
| Storage Procedures | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
| Stability / Shelf Life | 12 months at -20°C. 1 month at 4°C. |
| Applications | CD73 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000. |
| Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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HA-tag Peptide ant-101 Mouse Anti HA-tag peptide
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HAX1 ant-446 Mouse Anti Human HCLS1-associated protein X-1
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HOMER1 ant-357 Mouse Anti Human Homer Homolog-1
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IgA 1&2 ant-201 Mouse Anti Human IgA 1&2
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KLF4 ant-434 Mouse Anti Human Krueppel-like factor 4
KRT18 ant-025 Mouse Anti Human Cytokeratin 18
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MRSA ant-198 Mouse Anti Methicillin-Resistant Staphylococcus Aureus
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NDE1 ant-078 Mouse Anti Human nudE Nuclear Distribution Gene E Homolog 1
NELL2 ant-030 Mouse Anti Human NEL-Like 2
NFATC1 ant-436 Mouse Anti Human Nuclear factor of activated T-cells cytoplasmic 1
NKp30 ant-402 Mouse Anti Human Natural killer cell p30-related protein
NKp44 ant-401 Mouse Anti Human Natural killer cell p44-related protein
NKp46 ant-303 Mouse Anti Human Natural Cytotoxicity Receptor NKp46
NRAS ant-047 Mouse Anti Human Neuroblastoma RAS Viral Oncogene Homolog
OAT ant-013 Mouse Anti Human Ornithine aminotransferase
p53 ant-192 Recombinant Anti p53 scFv
p53 ant-228 Mouse Anti p53
PAP-1 ant-218 Polyclonal Rabbit Anti Human Pancreatitis-associated protein
PARK7 ant-317 Mouse Anti Human Parkinson Disease Protein 7
PCNA ant-341 Mouse Anti Human Proliferating Cell Nuclear Antigen
PDCD1 ant-417 Mouse Anti Human Programmed Cell Death 1
PDCD12 ant-457 Mouse Anti Human Programmed Cell Death 12
PDCD4 ant-338 Mouse Anti Human Programmed Cell Death 4
PDPN ant-343 Mouse Anti Human Podoplanin
PDX-1 ant-162 Polyclonal Rabbit Anti Pancreas Duodenum Homeobox-1
PGP9.5 ant-335 Mouse Anti Human PGP9.5
PLP ant-200 Mouse Anti Porteolipid Protein of Myelin
PSMA ant-450 Mouse Anti Human Prostate Specific Cancer Antigen
RAB5A ant-337 Mouse Anti Human RAB5A
Rac2 ant-067 Mouse Anti Human Ras-Related C3 Botulinum Toxin Substrate 2
RASSF1A ant-400 Mouse Anti Human Ras association domain-containing protein 1
REXO1 ant-413 Mouse Anti Human RNA exonuclease 1 homolog
SERPINB5 ant-364 Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5
SNAP25 ant-336 Mouse Anti Human Synaptosomal-associated protein 25
SNCA ant-315 Mouse Anti Human Alpha-Synuclein
SNCB ant-454 Polyclonal Rabbit Anti Human Beta-Synuclein
SNCG ant-455 Polyclonal Rabbit Anti Human Gamma-Synuclein
Streptavidin ant-345 Mouse Anti Streptavidin
SUMO2/3 ant-016 Mouse Anti Human Small Ubiquitin-Related Modifier 2/3
TARDBP ant-420 Mouse Anti Human TAR DNA-binding protein 43
TBCA ant-362 Mouse Anti Human Tubulin Folding Cofactor A
Tetanus ant-195 Recombinant Anti-Tetanus Toxoid scFv
TGFBI ant-349 Mouse Anti Human Transforming Growth Factor Beta Induced
TLR2 ant-408 Mouse Anti Human Toll-like receptor 2
TLR7 ant-403 Mouse Anti Human Toll-like receptor 7
TMEFF2 ant-428 Mouse Anti Human Tomoregulin-2
TOLLIP ant-430 Mouse Anti Human Toll-interacting protein
TPD52L1 ant-302 Mouse Anti Human Tumor Protein D52 L1
TREM2 ant-429 Mouse Anti Human Triggering receptor expressed on myeloid cells 2
TTR ant-003 Mouse Anti Human Transthyretin
TUBB2b ant-019 Mouse Anti Human Tubulin beta-2B chain
VAMP2 ant-334 Mouse Anti Human Synaptobrevin-2
VAMP3 ant-352 Mouse Anti Human Synaptobrevin-3
VHL ant-316 Mouse Anti Human Von Hippel-Lindau Protein
Vimentin ant-245 Mouse Anti Human Vimentin
Vimentin Biotin ant-246 Mouse Anti Human Vimentin Biotinylated
Vimentin FITC ant-247 Mouse Anti Human Vimentin FITC
WNT3A ant-431 Mouse Anti Human Protein Wnt-3a
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